Jesse Stimpson, North Carolina State University


A Modeling Study of Idiopathic Intracranial Hypertension


Abstract: In an attempt to better understand Idiopathic Intracranial Hypertension (IIH), mathematical models display the behavior of the brainÕs sinuses when introduced to changes in transmural pressure. The definite causes and proper treatment of IIH escape doctors and scientists. Disturbances of the brainÕs blood flow system, such as sudden pressure changes, may be the origin of this disorder. We consider a compartmental differential equation model, which describes the dynamics of pressure changes on the brainÕs sinuses and surrounding regions. Such changes may cause a partial collapse of the sinus, thus causing increased resistance to natural blood flow.

Advisor: Scott A. Stevens (Penn State Erie, the Behrend College)

Work done at: Penn State University, the Behrend College